UMR 7238 CNRS
Universite Pierre et Marie Curie
About
This website contains a set of tools and data sets that can be used to analyze the aggregation of a set of genes along the genome coordinate, at
different scales of observation. It is based for the moment on the
Escherichia coli genome.
It is useful to discover correlations between different sources of
data (e.g. expression, binding, or genomic data) and genome
organization. It implements most of the analyses performed in ref. (Scolari et al.
Molecular BioSystems 7, 878-888 2011)
on arbitrary data sets, using a web interface and improved algorithms.
Credits
Vittore F Scolari (vittore.scolari_at_upmc.fr)
Mina Zarei
Matteo Osella
Marco Cosentino Lagomarsino
Citation
NuST: analysis of the interplay between nucleoid organization
and gene expression. Bioinformatics. 2012 Jun 15;28(12):1643-4. doi:
10.1093/bioinformatics/bts201
See also
V. F. Scolari, B. Bassetti, B. Sclavi and M. Cosentino Lagomarsino.
Gene clusters reflecting macrodomain structure respond to nucleoid perturbations.
Molecular BioSystems. 7.3 (2011):878-888. doi:
10.1039/C0MB00213E
M. Zarei, B. Sclavi and M. Cosentino Lagomarsino.
Gene silencing and large-scale domain structure of the E. coli genome.
Molecular BioSystems. (2013). doi:
10.1039/C3MB25364C
Genophysique / Genomic Physics Group
UMR 7238 CNRS Universite Pierre et Marie Curie
Paris, France
Grant RGY-0069/2009-C