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LEVELNET is a versatile and interactive tool with a user-friendly web-interface designed for visualising, exploring and comparing protein-protein interaction (PPI) networks inferred from different types of evidence. It helps to break down the complexity of PPI networks by representing them as multi-layered graphs and by facilitating the direct comparison of their subnetworks toward biological interpretation. It focuses primarily on the protein chains whose 3D structures are available in the Protein Data Bank.

LEVELNET provides a unique opportunity for experimental and computational biologists to investigate whether and how a group of proteins establish physical contacts. It also provides a way to integrate and compare multiple PPI networks, assess predicted PPIs, or compile benchmark sets for training and testing predictive methods on PPI-related tasks.

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