Two of our alumni, Vittore Scolari, PhD student at LCQB, and Riccardo Vicedomini, postdoc, have been recognized this year by the CNRS with two permanent researcher positions! In 2021, Edoardo Sarti, postdoc at LCQB, was offered a permanent researcher position at INRIA.

Congratulations to all!

See the new highlight on ActuIA for our work on protein functional classification.

A novel computational approach to explore and classify functional diversity in genomic sequences. See the new article appeared in Molecular Biology and Evolution from the Analytical Genomics team.

Read the press release at Sorbonne Université and the CNRS

The Île-de-France Region has defined its 9 new major areas of research and innovation for the next 5 years, in which €100M will be invested.

Among them:

► AI4IDF - Intelligence artificielle centrée sur l’humain en Île-de-France, lead by Inria - PIs: Isabelle Ryl
► BIOCONS - Bioconvergence pour la santé, lead by Université de Paris Cité - PIs: Amanda Sylva Brun and Ariel Lindner

The LCQB participates in both programs.

New coverage on DNA storage in the Canadian TV and France 24

Towards predicting new mutations in SARS-CoV-2: in the very early stages of an emerging viral outbreak, can we predict new mutations in the proteins of the virus which might lead to its future variants? The "Statistical Genomics and Biological Physics" team proposes a computational approach based on a single viral genome infecting humans and pre-existing viral genomes infecting other species.

For more information see:

• the paper
• the press release of SU
• the news in FranceCulture

Gene duplication is a major source of functional diversification. However, the co-existence of two paralogues with similar biochemical properties but diverging functions can lead to potentially detrimental competition between the duplicates. This phenomenon has been named “paralogue interference”. In a recent article published in "Frontiers in cellular infection and microbiology, the "genetics networks" team of LCQB has addressed this question in the human pathogen Candida glabrata. They showed that evolution selected mutations which decreased competition between two, potentially interfering, transcription factors, thus allowing the emergence of the particular modes of regulation for respiration and iron homeostasis observed in extent Saccharomycetaceae species.

Link to the article