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Igor Rouzine
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The evolutionary origin of the universal distribution of mutation fitness effect. PLoS Comput Biol. 17(3), (2021).
. An evolution-based high-fidelity method of epistasis measurement: Theory and application to influenza. PLOS PathogensPLOS Pathogens. 17(6), pp.e1009669 - (2021).
. . An evolutionary model of progression to AIDS. Microorganisms 2020. 8(11), (2020).
. Mathematical models of evolution. One-locus theory, multi-locus theory, and applications to virus evolution. in Series in Mathematics and Life Sciences. Edited by: Anna Marciniak-Czochra, Benoît Perthame and Jean-Philippe Vert. De Gruyter. (2020)
Epistasis detectably alters correlations between genomic sites in a narrow parameter window. PLOS ONE. 14, pp.1-16 (2019).
. Antigenic evolution of viruses in host populations. PLoS Pathogens. 14, pp.e1007291 (2018).
. Evolutionary footprint of epistasis. PLOS Computational Biology. 14, pp.e1006426 (2018).
. Variability in viral pathogenesis: modeling the dynamic of acute and persistent infections. Curr Opin Virol. 23, pp.120-124 (2017).
. Conflicting Selection Pressures Will Constrain Viral Escape from Interfering Particles: Principles for Designing Resistance-Proof Antivirals. PLoS Comput Biol. 12(5), pp.e1004799 (2016).
. RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence. Cell Host Microbe. 19(4), pp.493-503 (2016).
. An evolutionary role for HIV latency in enhancing viral transmission. Cell. 160(5), pp.1002-12 (2015).
. A hardwired HIV latency program. Cell. 160(5), pp.990-1001 (2015).
. Fifteen years later: hard and soft selection sweeps confirm a large population number for HIV in vivo. PLoS Genet. 10(2), pp.e1004179 (2014).
. The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations. PLoS Comput Biol. 10(10), pp.e1003878 (2014).
. Stochastic variability in HIV affects viral eradication. Proc Natl Acad Sci U S A. 111(37), pp.13251-2 (2014).
. Design requirements for interfering particles to maintain coadaptive stability with HIV-1. J Virol. 87(4), pp.2081-93 (2013).
. The quantitative theory of within-host viral evolution. Journal of Statistical Mechanics: Theory and Experiment. 2013, pp.P01009 (2013).
. Reply to “Coadaptive Stability of Interfering Particles with HIV-1 When There Is an Evolutionary Conflict”. Journal of virology. 87, pp.9960–9962 (2013).
. Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations. Proc Natl Acad Sci U S A. 109(13), pp.4950-5 (2012).
. Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection. Proc Natl Acad Sci U S A. 108(14), pp.5661-6 (2011).
. Model with two types of CTL regulation and experiments on CTL dynamics. J Theor Biol. 263(3), pp.369-84 (2010).
. Multi-site adaptation in the presence of infrequent recombination. Theoretical population biology. 77, pp.189–204 (2010).
. Rapid adaptive amplification of preexisting variation in an RNA virus. J Virol. 82(9), pp.4354-62 (2008).
. The stochastic edge in adaptive evolution. Genetics. 179(1), pp.603-20 (2008).
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