Elodie Laine

Laine E, Carbone A*. Local Geometry and Evolutionary Conservation of Protein Surfaces Reveal the Multiple Recognition Patches in Protein-Protein Interactions. PLoS Comput Biol. 11(12), pp.e1004580 (2015).

Gomes PDa Silva F, Panel N, Laine E, Pascutti PGelado, Solary E, Tchertanov L. Differential Effects of CSF-1R D802V and KIT D816V Homologous Mutations on Receptor Tertiary Structure and Allosteric Communication. PLOS ONE. 9(5), (2014).

Couvé S, Ladroue C, Laine E, Mahtouk K, Guégan J, Gad S, Le Jeune H, Le Gentil M, Nuel G, Kim WY, Lecomte B, Pagès J-C, Collin C, Lasne F, Benusiglio PR, de Paillerets BBressac-, Feunteun J, Lazar V, Gimenez-Roqueplo A-P, Mazure NM, Dessen P, Tchertanov L, Mole DR, Kaelin W, Ratcliffe P, Richard S, Gardie B. Genetic Evidence of a Precisely Tuned Dysregulation in the Hypoxia Signaling Pathway during Oncogenesis. Cancer Res. 74(22), pp.6554-64 (2014).

de Beauchêne IChauvot, Allain A, Panel N, Laine E, Trouvé A, Dubreuil P, Tchertanov L. Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity. PLoS Comput Biol. 10(7), pp.e1003749 (2014).

Laine E, Carbone A* Identification of Protein Interaction Partners from Shape Complementarity Molecular Cross-Docking. in IEEE International Conference on Image Analysis and Processing (ICIAP) 2013 Workshops, LNCS 8158. Springer. pp. 318–325 (2013)

Lopes A, Sacquin-Mora S, Dimitrova V, Laine E, Ponty Y, Carbone A*. Protein-protein interactions in a crowded environment: an analysis via cross-docking simulations and evolutionary information. PLoS Comput Biol. 9(12), pp.e1003369 (2013).

Laine E, Auclair C, Tchertanov L. Allosteric communication across the native and mutated KIT receptor tyrosine kinase. PLoS Comput Biol. 8(8), pp.e1002661 (2012).

Laine E, Goncalves C, Karst JC, Lesnard A, Rault S, Tang W-J, Malliavin TE, Ladant D, Blondel A. Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor. Proc Natl Acad Sci U S A. 107(25), pp.11277-82 (2010).