Elodie Laine

Corsi F, Lavery R, Laine E, Carbone A. Multiple protein-DNA interfaces unravelled by evolutionary information, physico-chemical and geometrical properties. PLoS Computational Biology. 16(2), (2020).

Grudinin S, Laine E, Hoffmann A. Predicting Protein Functional Motions: an Old Recipe with a New Twist. Biophysical Journal. (2020).

Karami Y, Saighi P, Vanderhaegen R, Gerlier D, Longhi S, Laine E, Carbone A. Predicting substitutions to modulate disorder and stability in coiled-coils. BMC Bioinformatics. 21(573 ), (2020).

Ait-hamlat A, Zea DJavier, Labeeuw A, Polit L, Richard H, Laine E. Transcripts’ Evolutionary History and Structural Dynamics Give Mechanistic Insights into the Functional Diversity of the JNK Family. Journal of Molecular Biology. (2020).

Lensink MF, Brysbaert G, Nadzirin N, Velankar S, Chaleil RAG, Gerguri T, Bates PA, Laine E, Carbone A, Grudinin S, Kong R, Liu R-R, Xu X-M, Shi H, Chang S, Eisenstein M, Karczynska A, Czaplewski C, Lubecka E, Lipska A, Krupa P, Mozolewska M, Golon Ł, Samsonov S, Liwo A, Crivelli S, Pagès G, Karasikov M, Kadukova M, Yan Y, Huang S-Y, Rosell M, Rodríguez-Lumbreras LAngel, Romero-Durana M, Díaz-Bueno L, Fernandez-Recio J, Christoffer C, Terashi G, Shin W-H, Aderinwale T, Subraman SRaghavendr, Kihara D, Kozakov D, Vajda S, Porter K, Padhorny D, Desta I, Beglov D, Ignatov M, Kotelnikov S, Moal IH, Ritchie DW, de Beauchêne IChauvot, Maigret B, Devignes M-D, Echartea MElisa Ruiz, Barradas-Bautista D, Cao Z, Cavallo L, Oliva R, Cao Y, Shen Y, Baek M, Park T, Woo H, Seok C, Braitbard M, Bitton L, Scheidman-Duhovny D, DapkŪnas J, Olechnovič K, Venclovas Č, Kundrotas PJ, Belkin S, Chakravarty D, Badal VD, Vakser IA, Vreven T, Vangaveti S, Borrman T, et al.. Blind prediction of homo- and hetero- protein complexes: The CASP13-CAPRI experiment. Proteins: Structure, Function, and BioinformaticsProteins: Structure, Function, and BioinformaticsProteins. (ja), (2019).

Dequeker C, Laine E, Carbone A. Decrypting protein surfaces by combining evolution, geometry and molecular docking. Proteins. (2019).

Laine E, Karami Y, Carbone A. GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects. Molecular Biology and Evolution. (2019).

Karami Y, Bitard-Feildel T, Laine E, Carbone A. "Infostery” analysis of short molecular dynamics simulations identifies highly sensitive residues and predicts deleterious mutations. Scientific Reports. 8(1), (2018).

Raucci R, Laine E, Carbone A. Local Interaction Signal Analysis predicts protein-protein binding affinity. Structure. (2018).

Abdollahi N, Albani A, Anthony E, Baud A, Cardon M, Clerc R, Czernecki D, Conte R, David L, Delaune A, Djerroud S, Fourgoux P, Guiglielmoni N, Laurentie J, Lehmann N, Lochard C, Montagne R, Myrodia V, Opuu V, Parey E, Polit L, Privé S, Quignot C, Ruiz-Cuevas M, Sissoko M, Sompairac N, Vallerix A, Verrecchia V, Delarue M, Guérois R, Ponty Y, Sacquin-Mora S, Carbone A, Froidevaux C, Le Crom S, Lespinet O, Weigt M, Abboud S, Bernardes JS, Bouvier G, Dequeker C, Ferré A, Fuchs P, Lelandais G, Poulain P, Richard H, Schweke H, Laine* E, Lopes* A. Meet-U: Educating through research immersion. PLOS Computational Biology. 14, pp.1-10 (2018).

Laine E Decrypting how protein move and change their shape. in Proceeding of 16th International Symposium on Mathematical and Computational Biology. Edited by: Rubem P Mondaini (Federal University of Rio de Janeiro, Brazil). Nankai University, Tianjin, China, 30th Oct. – 5th Nov. 2016. Chern Institute of Mathematics. (2017)

Dequeker C, Laine E, Carbone A. INTerface Builder: a fast protein-protein interface reconstruction tool. J Chem Inf Model. (2017).

Laine E, Carbone A. Protein social behaviour makes a stronger signal for partner identification than surface geometry. Proteins. 85(1), pp.137-154 (2017).

Champeimont R, Laine E, Hu S-W, Penin F, Carbone A. Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins. Scientific Reports. 6, (2016).

Karami Y, Laine E, Carbone A. Dissecting protein architecture with communication blocks and communicating segment pairs. BMC Bioinformatics. 17, pp.133–148 (2016).

Ripoche H, Laine E, Ceres N, Carbone A. JET2 Viewer: a database of predicted multiple, possibly overlapping, protein-protein interaction sites for PDB structures. Nucleic Acids Research. (2016).

Delaveau T, Davoine D, Jolly A, Vallot A, Rouviere JO, Gerber A, Brochet S, Plessis M, Roquigny R, Merhej J, Leger T, Garcia C, Lelandais G, Laine E, Palancade B, Devaux F, Garcia M. Tma108, a putative M1 aminopeptidase, is a specific nascent chain-associated protein in Saccharomyces cerevisiae. Nucleic Acids Res. 44(18), pp.8826-8841 (2016).

Laine E, Carbone A. Local Geometry and Evolutionary Conservation of Protein Surfaces Reveal the Multiple Recognition Patches in Protein-Protein Interactions. PLoS Comput Biol. 11(12), pp.e1004580 (2015).

Gomes PDa Silva F, Panel N, Laine E, Pascutti PGelado, Solary E, Tchertanov L. Differential Effects of CSF-1R D802V and KIT D816V Homologous Mutations on Receptor Tertiary Structure and Allosteric Communication. PLOS ONE. 9(5), (2014).

Couvé S, Ladroue C, Laine E, Mahtouk K, Guégan J, Gad S, Le Jeune H, Le Gentil M, Nuel G, Kim WY, Lecomte B, Pagès J-C, Collin C, Lasne F, Benusiglio PR, de Paillerets BBressac-, Feunteun J, Lazar V, Gimenez-Roqueplo A-P, Mazure NM, Dessen P, Tchertanov L, Mole DR, Kaelin W, Ratcliffe P, Richard S, Gardie B. Genetic Evidence of a Precisely Tuned Dysregulation in the Hypoxia Signaling Pathway during Oncogenesis. Cancer Res. 74(22), pp.6554-64 (2014).

de Beauchêne IChauvot, Allain A, Panel N, Laine E, Trouvé A, Dubreuil P, Tchertanov L. Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity. PLoS Comput Biol. 10(7), pp.e1003749 (2014).

Laine E, Carbone A Identification of Protein Interaction Partners from Shape Complementarity Molecular Cross-Docking. in IEEE International Conference on Image Analysis and Processing (ICIAP) 2013 Workshops, LNCS 8158. Springer. pp. 318–325 (2013)

Lopes A, Sacquin-Mora S, Dimitrova V, Laine E, Ponty Y, Carbone A. Protein-protein interactions in a crowded environment: an analysis via cross-docking simulations and evolutionary information. PLoS Comput Biol. 9(12), pp.e1003369 (2013).

Laine E, Auclair C, Tchertanov L. Allosteric communication across the native and mutated KIT receptor tyrosine kinase. PLoS Comput Biol. 8(8), pp.e1002661 (2012).

Laine E, Goncalves C, Karst JC, Lesnard A, Rault S, Tang W-J, Malliavin TE, Ladant D, Blondel A. Use of allostery to identify inhibitors of calmodulin-induced activation of Bacillus anthracis edema factor. Proc Natl Acad Sci U S A. 107(25), pp.11277-82 (2010).