The Laboratory of Computational and Quantitative Biology (LCQB), headed by A. Carbone, is an interdisciplinary laboratory working at the interface between biology and quantitative sciences. It is built to promote a balanced interaction of theoretical and experimental approaches in biology and to foster the definition of new experimental questions, data analysis and modeling of biological phenomena. Our projects address questions on biological structures and processes through the gathering of experimental measures, the in silico generation of new biological data that remain inaccessible to experiments today (modeling of biological systems), the development of statistical methods for data analysis, and the conception of original algorithms aimed to predictions. The lab is supported by the CNRS and Sorbonne Université.

News

November 7, 2014

Alice Coucke, Eleonora De Leonardis and Matteo Figliuzzi (Statistical Genomics Group) and Vittore Scolari (Genomic Physics Group) co-organize the 2nd edition of the conference:
Paris Biological Physics Community Day 2014

The conference will be held at Centre Culturel Irlandais in Paris

October 8-10, 2014

The international meeting "Protein-Protein Interactions on the Genome Scale" is organized within the framework of the MAPPING project (Investissement d'Avenir en Bioinformatique) by A.Carbone.
The event will take place at UPMC, Jussieu Campus.
Registrations are open.

July 15-August 8, 2014

A.Carbone and E.Laine, from the Analytical Genomics Team, organize the ICS Summer School 2014 "Scientific Trends at the Interfaces - Bioinformatics and Scientific Visualization". Information on the school can be downloaded here.

March 28, 2014

The Biology of Genomes team participated to the complete design and synthesis of the first eukaryotic synthetic chromosome. We compared replication dynamics of synthetic and native chromosome III and saw few dramatic changes in spite of several autonomously replicating sequences having been deleted.

Total Synthesis of a Functional Designer Eukaryotic Chromosome. Annaluru, Muller et al., Science (2014) DOI:10.1126/science.1249252

February 8, 2014

A World Community Grid Lecture Series webcast describing the work done by the team and its collaborators on protein-protein interactions, within the framework of the "Help Cure Muscular Dystrophy" project can be found here.

January 23-24, 2014

Hugues Richard co-organizes the 10th edition of the workshop: Statistical Methods for (Post-) Genomics Data (SMPGD). 

The Laboratory Genomics of Microorganisms will hosts the meeting at the UPMC main campus, Paris, France.

December 24, 2013

Gherardi M, Mandrà S, Bassetti B, Cosentino Lagomarsino M, "Evidence for soft bounds in Ubuntu package sizes and mammalian body masses"

Proc Natl Acad Sci USA. 2013 Dec 24;110(52):21054-8.

December 12-13, 2013

Marco Cosentino Lagomarsino co-organizes the 2nd edition of Quantitative Methods in Gene Regulation

December 3, 2013

Vittore Scolari (Genomic Physics group) and Alice Coucke (Statistical Genomics team) co-organize the 1th edition of the conference:
Paris Biological Physics Community Day 2013 
The conference will be hosted at Centre Culturel Irlandais in Paris.

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