The Laboratory of Computational and Quantitative Biology (LCQB), headed by A. Carbone, is an interdisciplinary laboratory working at the interface between biology and quantitative sciences. It is built to promote a balanced interaction of theoretical and experimental approaches in biology and to foster the definition of new experimental questions, data analysis and modeling of biological phenomena. Our projects address questions on biological structures and processes through the gathering of experimental measures, the in silico generation of new biological data that remain inaccessible to experiments today (modeling of biological systems), the development of statistical methods for data analysis, and the conception of original algorithms aimed to predictions. The lab is supported by the CNRS and Sorbonne Université.


October 28, 2013

The Analytical Genomics team releases the complete cross docking data of Mintseris Benchmark 2.0.

The analysis will are available in the article:

Anne Lopes,  Sophie Sacquin-Mora, Viktoriya Dimitrova, Elodie Laine, Yann Ponty, Alessandra Carbone. Protein-Protein Interactions in a Crowded Environment: An Analysis via Cross-Docking Simulations and Evolutionary Information. PLOS computational Biology (2013).

The dataset of protein-protein interactions was produced with over 7 months of computations on World Community Grid and with the help of thousands of internautes providing their computer time to dock about 300000 conformations per protein pair in the set of 28224 possible pairs in the Mintseris dataset.

October 10-11, 2013

The 3rd Cross Disciplinary Genomics meeting "Biological networks: current and future challenges" will be held at UPMC, in the Jussieu Campus.

There is no participation fee but registration is required.

July 1, 2013

Alessandra Carbone has been elected Senior Member at the Institut Universitaire de France.

June 1, 2013

The project COEVSTAT (co-PI Martin Weigt, Statistical Genomics and Biological Physics team) has been selected for funding by the Agence Nationale de la Recherche (ANR).

April 12, 2013

Marco Cosentino-Lagomarsino organizes the upcoming "Fifth Journée Darwin", at Institut Henri Poincaré, April 12, 2013, 10h - Amphithéâtre Hermite, Paris, France.

April 1, 2013

A PhD scholarship has been allocated by the Institut des Systèmes Complexes to the Statistical Genomics and Biological Physics team (co-direction with R. Monasson, LPTENS)


Open Positions