Article

EJ Molinelli, A Korkut, W Wang, ML Miller, NP Gauthier, X Jing, P Kaushik, Q He, G Mills, DB Solit, CA Pratilas, M Weigt, A Braunstein, A Pagnani, R Zecchina, C Sander, "Perturbation Biology: Inferring Signaling Networks in Cellular Systems", PLoS Comp. Biol. 9(12): e1003290 (2013).

The Analytical Genomics team releases the complete cross docking data of Mintseris Benchmark 2.0.

The analysis will are available in the article:

Anne Lopes,  Sophie Sacquin-Mora, Viktoriya Dimitrova, Elodie Laine, Yann Ponty, Alessandra Carbone. Protein-Protein Interactions in a Crowded Environment: An Analysis via Cross-Docking Simulations and Evolutionary Information. PLOS computational Biology (2013).

The dataset of protein-protein interactions was produced with over 7 months of computations on World Community Grid and with the help of thousands of internautes providing their computer time to dock about 300000 conformations per protein pair in the set of 28224 possible pairs in the Mintseris dataset.

S. Cocco, R. Monasson, M. Weigt, "From principal component to direct coupling analysis of coevolution in proteins: Low-eigenvalue modes are needed for structure prediction", PLoS Comp. Biol. 9(8): e1003176 (2013).

The Analytical Genomics team published: A.Mathelier and A.Carbone, Large scale chromosomal mapping of human microRNA structural clusters, Nucleic Acids Research, in press.

The Analytical Genomics team has a feature article in International Science Grid This Week: Desktop power helps map protein dance

The Diatom Genomics team (M.Huysman, A.Fortunato, A.Falciatore) and collaborators at the University of Ghent published a paper:

M.J.J. Huysman, A.E. Fortunato, M.Matthijs, B.Schellenberger Costa, R.Vanderhaeghen, H.Van den Daele, M.Sachse, D.Inzé, C.Bowler, P.G. Kroth, C.Wilhelm, A.Falciatore, W.Vyverman and L.De Veylder (2013) AUREOCHROME1a-Mediated Induction of the Diatom-Specific Cyclin dsCYC2 Controls the Onset of Cell Division in Diatoms (Phaeodactylum tricornutum), Plant Cell, in press, 2013.